Increased Oxidant Activity Mediates Vascular Dysfunction in Vibration Injury
نویسندگان
چکیده
منابع مشابه
Increased oxidant activity mediates vascular dysfunction in vibration injury.
Occupational exposure to hand-operated vibrating tools causes a spectrum of pathological changes in the vascular, neurological, and musculoskeletal systems described as the hand-arm vibration syndrome (HAVS). Experiments were performed to determine the effects of acute vibration on the function of digital arteries. Rats paws were exposed to a vibrating platform (4 h, 125 Hz, constant accelerati...
متن کاملJpet #144618 1 Title Page Increased Oxidant Activity Mediates Vascular Dysfunction in Vibration Injury
Occupational exposure to hand-operated vibrating tools causes a spectrum of pathological changes in the vascular, neurological and musculoskeletal systems described as the Hand-Arm Vibration Syndrome (HAVS). Experiments were performed to determine the effects of acute vibration on the function of digital arteries. Rats paws were exposed to a vibrating platform (4 hrs, 125 Hz, constant accelerat...
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Increases in arginase activity have been reported in a variety of disease conditions characterized by vascular dysfunction. Arginase competes with NO synthase for their common substrate arginine, suggesting a cause and effect relationship. We tested this concept by experiments with streptozotocin diabetic rats and high glucose (HG)-treated bovine coronary endothelial cells (BCECs). Our studies ...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2009
ISSN: 0741-5214
DOI: 10.1016/j.jvs.2009.07.010